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Ciclosporin is indicated to treat and prevent graft-versus-host disease in bone marrow transplantation and to prevent rejection of kidney, heart, and liver transplants. [8] [7] It is also approved in the US for treating of rheumatoid arthritis and psoriasis, persistent nummular keratitis following adenoviral keratoconjunctivitis, [25] [7] and as eye drops for treating dry eyes caused by ...
The US Food and Drug Administration has approved cyclosporine for the management of severe plaque psoriasis in immunocompetent individuals. [27] Cyclosporine is regarded as an essential first-line medication for the management of unstable cases of psoriatic erythroderma because of its quick onset of action. [23]
November 14 – The immunosuppressant cyclosporine is approved by the FDA, leading to a revolution in the field of transplantation. November 16 – A jury in Gretna, Louisiana acquits Ginny Foat of the murder of Argentine businessman Moses Chaiyo.
This page was last edited on 13 July 2011, at 16:40 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may ...
November 14 – The immunosuppressant cyclosporine is approved by the FDA, leading to a revolution in the field of transplantation. November 15 – The Turkish part of Cyprus declares independence. November 17 – The Zapatista Army of National Liberation is founded in Mexico.
The first coincidence was that etoposide and cyclosporine were both found and developed on the chemical and biological side by the same groups, those of the present authors and their specific biological effects were discovered by one of us; second, both compounds were approved by the United States Food and Drug Administration on the same day in ...
Voclosporin, sold under the brand name Lupkynis, is a calcineurin inhibitor used as an immunosuppressant medication for the treatment of lupus nephritis. [2] [4] It is an analog of ciclosporin that has enhanced action against calcineurin and greater metabolic stability.
Muromonab-CD3 was approved by the U.S. Food and Drug Administration (FDA) in 1986, [5] making it the first monoclonal antibody to be approved anywhere as a drug for humans. In the European Communities , it is the first drug to be approved under the directive 87/22/EWG, a precursor of the European Medicines Agency (EMA) centralised approval ...
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