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Hypersensitivity (also called hypersensitivity reaction or intolerance) is an abnormal physiological condition in which there is an undesirable and adverse immune response to an antigen. [ 1 ] [ 2 ] It is an abnormality in the immune system that causes immune diseases including allergies and autoimmunity .
Sensory processing sensitivity (SPS) is a temperamental or personality trait involving "an increased sensitivity of the central nervous system and a deeper cognitive processing of physical, social, and emotional stimuli". [2]
Sensory processing disorder; Other names: Sensory integration dysfunction: An SPD nosology proposed by Miller LJ et al. (2007) [1] Specialty: Psychiatry, occupational therapy, neurology: Symptoms: Hypersensitivity and hyposensitivity to stimuli, and/or difficulties using sensory information to plan movement. Problems discriminating ...
Type IV hypersensitivity, in the Gell and Coombs classification of allergic reactions, often called delayed-type hypersensitivity, is a type of hypersensitivity reaction that can take a day or more to develop. [1] Unlike the other types, it is not humoral (not antibody-mediated) but rather is a type of cell-mediated response.
Type III hypersensitivity, in the Gell and Coombs classification of allergic reactions, occurs when there is accumulation of immune complexes (antigen-antibody complexes) that have not been adequately cleared by innate immune cells, giving rise to an inflammatory response and attraction of leukocytes.
Type I hypersensitivity (or immediate hypersensitivity), in the Gell and Coombs classification of allergic reactions, is an allergic reaction provoked by re-exposure to a specific type of antigen referred to as an allergen. [1] Type I is distinct from type II, type III and type IV hypersensitivities. The relevance of the Gell and Coombs ...
The hypersensitivity of people with PTSD to sensory stimuli is supported by an augmented P300 event-related potential response compared to healthy controls which indicates a semi-permanent heightened attention to deviant and salient stimuli. [9] Obsessive–compulsive disorder (OCD) [11]
Later, it became clear that several different disease mechanisms were implicated, with a common link to a disordered activation of the immune system. In 1963, a new classification scheme was designed by Philip Gell and Robin Coombs that described four types of hypersensitivity reactions, known as Type I to Type IV hypersensitivity. [165]