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High doses of spironolactone, which are needed for considerable antiandrogenic effects, are not recommended for men due to the high risk of feminization and other side effects. Spironolactone can be used to treat symptoms of hyperandrogenism , such as due to polycystic ovary syndrome .
Spironolactone has shown no significant effect on levels of testosterone, estradiol, luteinizing hormone, and follicle-stimulating hormone in men. [ 146 ] [ 78 ] No or only small changes in cortisol levels have been observed in clinical studies with spironolactone.
And because PCOS affects many hormones (example: estrogen) that are responsible for a variety of bodily functions, women with PCOS may also find it hard to become pregnant.
Hyperandrogenism affects 5–10% of women of reproductive age. [11] Hyperandrogenism can affect both men and women but is more noticeable in women since elevated levels of androgens in women may facilitate virilization. Because hyperandrogenism is characterized by elevated male sex hormone levels, symptoms of hyperandrogenism in men are often ...
Spironolactone. Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS.
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In any case, common side effects of antiandrogens in men include breast tenderness, breast enlargement, feminization, hot flashes, sexual dysfunction, infertility, and osteoporosis. In women, antiandrogens are much better tolerated , and antiandrogens that work only by directly blocking androgens are associated with minimal side effects.
Once on a GLP-1, hormones can return to normal and actually improve ovulation and fertility, including for people with polycystic ovarian syndrome (PCOS). GLP-1s also help control blood sugar ...
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related to: how does spironolactone affect hormones function in women over 60 men- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
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