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  2. Fibrinogen - Wikipedia

    en.wikipedia.org/wiki/Fibrinogen

    Fibrinogen (coagulation factor I) is a glycoprotein complex, produced in the liver, [1] that circulates in the blood of all vertebrates. [2] During tissue and vascular injury, it is converted enzymatically by thrombin to fibrin and then to a fibrin-based blood clot. Fibrin clots function primarily to occlude blood vessels to stop bleeding ...

  3. Euglobulin lysis time - Wikipedia

    en.wikipedia.org/wiki/Euglobulin_lysis_time

    The euglobulin lysis time (ELT) is a test that measures overall fibrinolysis.The test is performed by mixing citrated platelet-poor plasma with acid in a glass test tube. . This acidification causes the precipitation of certain clotting factors in a complex called the euglobulin fract

  4. Prothrombin time - Wikipedia

    en.wikipedia.org/wiki/Prothrombin_time

    PT measures the following coagulation factors: I (fibrinogen), II (prothrombin), V (proaccelerin), VII (proconvertin), and X (Stuart–Prower factor). PT is often used in conjunction with the activated partial thromboplastin time (aPTT) which measures the intrinsic pathway and common pathway of coagulation.

  5. Coagulation - Wikipedia

    en.wikipedia.org/wiki/Coagulation

    If a coagulation factor is part of the contact activation or tissue factor pathway, a deficiency of that factor will affect only one of the tests: Thus hemophilia A, a deficiency of factor VIII, which is part of the contact activation pathway, results in an abnormally prolonged aPTT test but a normal PT test. Deficiencies of common pathway ...

  6. Thrombin time - Wikipedia

    en.wikipedia.org/wiki/Thrombin_time

    The thrombin time (TT), also known as the thrombin clotting time (TCT), is a blood test that measures the time it takes for a clot to form in the plasma of a blood sample containing anticoagulant, after an excess of thrombin has been added. [1] It is used to diagnose blood coagulation disorders and to assess the effectiveness of fibrinolytic ...

  7. Thromboelastometry - Wikipedia

    en.wikipedia.org/wiki/Thromboelastometry

    EXTEM test mildly activates haemostasis via the physiological activator tissue factor. The result is influenced by extrinsic coagulation factors, platelets and fibrinogen. EXTEM is a screening test for the (extrinsic) haemostasis system. This assay is not influenced by heparin (heparin inhibitor included in the EXTEM reagent).

  8. Coagulation testing - Wikipedia

    en.wikipedia.org/wiki/Coagulation_testing

    Local tests characterize the results of work of the separate components of the blood coagulation system cascade, as well as of the separate coagulation factors. They are essential for the possibility to specify the pathology localization within the accuracy of coagulation factor. [citation needed]

  9. Fibrin - Wikipedia

    en.wikipedia.org/wiki/Fibrin

    Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platelets, forms a hemostatic plug or clot over a wound site.

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