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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4.. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
The dominant hosts for viruses in the ocean are marine microorganisms, such as bacteria. [14] Bacteriophages are harmless to plants and animals, and are essential to the regulation of marine and freshwater ecosystems [91] are important mortality agents of phytoplankton, the base of the foodchain in aquatic environments. [92]
The interaction of phage with bacteria is the primary concern of phage community ecologists. Bacteria have developed mechanisms that prevent phages from having an effect on them, which has led to this evolutionary arms race between the phages and their host bacteria. [14]
Biosynthesis – the phage DNA replicates inside the cell, synthesizing new phage DNA and proteins; Maturation – the replicated material assembles into fully formed viral phages (each made up of a head, a tail and tail fibers) Lysis - cell wall or membrane ruptures, disintegrating it and releasing the virus in the process
Phage therapy is the use of bacteriophages to treat bacterial infections. Bacteriophage treatment offers a possible alternative to conventional antibiotic treatments for bacterial infection. [55] It is conceivable that, although bacteria can develop resistance to phages, the resistance might be easier to overcome than resistance to antibiotics.
Bacteriophage T7 (or the T7 phage) is a bacteriophage, a virus that infects bacteria. It infects most strains of Escherichia coli and relies on these hosts to propagate. Bacteriophage T7 has a lytic life cycle , meaning that it destroys the cell it infects.
Phage typing is based on the specific binding of phages to antigens and receptors on the surface of bacteria and the resulting bacterial lysis or lack thereof. [4] The binding process is known as adsorption. [5] Once a phage adsorbs to the surface of a bacteria, it may undergo either the lytic cycle or the lysogenic cycle. [6]
Enterobacteria phage λ (lambda phage, coliphage λ, officially Escherichia virus Lambda) is a bacterial virus, or bacteriophage, that infects the bacterial species Escherichia coli (E. coli). It was discovered by Esther Lederberg in 1950. [ 2 ]