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Cholesterol synthesis appears to occur mostly at night, [140] so statins with short half-lives are usually taken at night to maximize their effect. Studies have shown greater LDL and total cholesterol reductions in the short-acting simvastatin taken at night rather than the morning, [141] [142] but have shown no difference in the long-acting ...
Statins with shorter half-lives are more effective when taken in the evening, so their peak effect occurs when the body's natural cholesterol production is at its highest. A recent meta-analysis suggested that statins with longer half-lives, including atorvastatin, may also be more effective at lowering LDL cholesterol if taken in the evening. [40]
Older adults over age 70 should consider taking statins, study finds. Corrie Pelc. September 17, 2024 at 8:15 AM. Research shows that statins may benefit those over the age of 70, too. BSIP/Getty ...
Fenofibrate (sold under the brand name Tricor among others), is an oral medication of the fibrate class used to treat abnormal blood lipid levels. [3] It is less commonly used compared to statins because it treats a different type of cholesterol abnormality to statins.
Part of the power of statins lies in the fact that they cause few side effects. “Generally, about 90 out of 100 people have no trouble with a stain,” says Dr. Blumenthal. These Are the Statin ...
Why statins are prescribed Women develop cardiovascular disease less often than men, according to a study published in 2023. However, they have a higher rate of death from cardiovascular disease.
Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people who take statin medications. [1] However, there are cases of SAAM in patients who have not taken statin medication, and this can be explained by the exposure to natural sources of statin ...
Up to 80% of athletes using statins experience significant adverse muscular effects, including cramps; [21] the rate appears to be approximately 10–25% in a typical statin-using population. [ 22 ] [ 23 ] In some cases, adverse effects disappear after switching to a different statin; however, they should not be ignored if they persist, as they ...
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