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Leptospirosis is treated with the antibiotics doxycycline and penicillin. [28] There are more than 200 diverse pathogenic Leptospira serovars, making it challenging to develop an effective vaccine. [31] However, vaccines for the serovars known as Hardjo, Pomona, Canicola, Grippotyphosa and icterohaemorrhagiae have been developed.
Leptospirosis is a blood infection caused by the bacteria Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild (headaches, muscle pains, and fevers) to severe (bleeding in the lungs or meningitis). [5]
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Leptospira (from Ancient Greek λεπτός (leptós) 'fine, thin, narrow, etc.' and Latin spira 'coil') [1] is a genus of spirochaete bacteria, including a small number of pathogenic and saprophytic species. [2]
Leptospira noguchii is another pathogenic bacteria that causes Leptospirosis. Leptospirosis can be transferred in a multitude of ways. Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7]
Marburg is a rare but “severe hemorrhagic fever that can cause serious illness and death,” the U.S. Centers for Disease Control says, adding that there is no treatment or vaccine for it.
A separate vaccine is available for protection against botulism if required. Leptospirosis vaccine is available as a double vaccine that protects against both L. hardjo and L. pomona bacterium, or is also available in a 7in1 vaccine that combines with the clostridial 5in1 vaccine into one vaccination. [8]