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Human betaherpesvirus 5, also called human cytomegalovirus (HCMV,HHV-5), [2] is a species of virus in the genus Cytomegalovirus, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is also commonly called CMV. [3]
Cidofovir (CDV) does not require initial phosphorylation for its antiviral action. Further phosphorylation to the triphosphate form of GCV and CDV is performed by cellular kinases. The nucleoside-triphosphate-analogues compete with the cellular nucleotide triphosphates at the viral polymerase pUL54 and are incorporated into the viral DNA.
Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness. [1] Caused by human cytomegalovirus , it occurs predominantly in people whose immune system has been compromised, including 15-40% of those with AIDS.
In the past nucleic acid tests have mainly been used as a secondary test to confirm positive serological results. [3] However, as they become cheaper and more automated, they are increasingly becoming the primary tool for diagnostics and can also be use for monitoring of treatment of viral infected individuals t.
The most studied is Human cytomegalovirus (HCMV), which is also known as Human betaherpesvirus 5 (HHV-5). Other primate CMV species include Chimpanzee cytomegalovirus (CCMV) that infects chimpanzees and orangutans , and Simian cytomegalovirus (SCCMV) and Rhesus cytomegalovirus (RhCMV) that infect macaques ; CCMV is known as both Panine beta ...
A static top four in this week’s College Football Playoff rankings will be followed by a series of key decisions involving one-, two- and three-loss teams.. Maybe the biggest debate will be ...
Bolivian ex-president Evo Morales told Reuters on Monday that the government of ally-turned-rival President Luis Arce was behind an alleged gun attack on his convoy, lashing out at what he called ...
Research conducted on cytomegalovirus (CMV) indicates that the viral human IL-10 homolog, cmvIL-10, is important in inhibiting pro-inflammatory cytokine synthesis. The cmvIL-10 protein has 27% identity with hIL-10 and only one conserved residue out of the nine amino acids that make up the functional site for cytokine synthesis inhibition on hIL-10.