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As the metabolism of testosterone in males is more pronounced, the daily production is about 20 times greater in men. [10] [11] Females are also more sensitive to the hormone. [12] [page needed] In addition to its role as a natural hormone, testosterone is used as a medication to treat hypogonadism and breast cancer. [13]
Testosterone can be taken by a variety of different routes of administration. [2] [3] These include oral, buccal, sublingual, intranasal, transdermal (gels, creams, patches, solutions), vaginal (creams, gels, suppositories), rectal (suppositories), by intramuscular or subcutaneous injection (in oil solutions or aqueous suspensions), and as a subcutaneous implant.
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor [9] that is activated by binding any of the androgenic hormones, including testosterone and dihydrotestosterone, [10] in the cytoplasm and then translocating into the nucleus.
As an anabolic (metabolism-related) hormone, testosterone plays a vital role in building and maintaining muscle mass. ... testosterone is an essential hormone for bone health and maintenance. If ...
A study published in the Journal of Clinical Endocrinology & Metabolism reported that today's average 30-year-old man has approximately 17 percent ... Testosterone is the primary male sex hormone ...
Research on women and testosterone has been limited, but as more is done, experts are seeing that the hormone affects the female sex drive, just as it does the male. It also plays an essential ...
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