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The amniotic sac, also called the bag of waters [1] [2] or the membranes, [3] is the sac in which the embryo and later fetus develops in amniotes. It is a thin but tough transparent pair of membranes that hold a developing embryo (and later fetus) until shortly before birth .
Tubes filled with amniotic fluid for amniocentesis. The amniotic fluid is the protective liquid contained by the amniotic sac of a gravid amniote.This fluid serves as a cushion for the growing fetus, but also serves to facilitate the exchange of nutrients, water, and biochemical products between mother and fetus.
Preterm premature rupture of membranes (PPROM) is when water breaks both before the onset of labor and before the pregnancy's 37 week gestation. [3] [4] In the United States, more than 120,000 pregnancies per year are affected by a premature rupture of membranes, which is the cause of about one third of preterm deliveries. [5]
Glucocorticoids have been implicated in fetal maturation, regulation of immune response and many other pregnancy associated changes. [15] As well as its function in parturition, Prostaglandin E2 is vital for fetal lung maturation. Additionally, there is an abundance of 11β-hydroxysteroid dehydrogenase 1 expressed in the foetal membranes.
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Tobacco use during pregnancy [10] Illicit drug use during pregnancy [11] Having had PROM or preterm delivery in previous pregnancies [8] Polyhydramnios: too much amniotic fluid [9] Multiple gestation: being pregnant with two or more fetuses at one time [8] Having had episodes of bleeding anytime during the pregnancy [8]
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