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Ruxolitinib (sold under the brand names Jakafi and Jakavi among others, and as Opzelura in cream form) is a medication used for the treatment of intermediate or high-risk myelofibrosis, [6] a type of myeloproliferative neoplasm that affects the bone marrow; [11] [12] polycythemia vera, when there has been an inadequate response to or intolerance of hydroxyurea; [6] [13] and steroid-refractory ...
SHENZHEN, CHINA, Sept. 24, 2024 (GLOBE NEWSWIRE) -- China Medical System Holdings Limited (the “Company”, together with its subsidiaries, the “Group” or “CMS”) is pleased to announce that on September 24, 2024, the New Drug Application (NDA) for vitiligo indication of ruxolitinib phosphate cream (the “ruxolitinib cream” or the “Product”) has been accepted by the National ...
Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure. [5] [6] Treatment options include topical medications, light therapy ...
Ruxolitinib (topical) Opzelura: JAK1, JAK2: September 2021 (US) Moderate-to-severe atopic dermatitis (not as a first-line therapy) Nonsegmental vitiligo [41] Pacritinib: Vonjo: JAK2: February 2022 (US) Primary and secondary myelofibrosis (intermediate or high-risk) with thrombocytopenia [42] Deucravacitinib: Sotyktu: TYK2: September 2022 (US)
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PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: vitiligo, eczema, psoriasis, graft-versus-host disease, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen.
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