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MDMA is an empathogenic-entactogenic and serotonergic psychotropic drug used primarily for recreational, though sometimes also therapeutic, purposes.Among users of MDMA, the serotonergic effects of the drug are often of particular interest and concern: After consuming MDMA, serotonin concentrations are greatly reduced in the brain. 5-HTP is necessary for serotonin production and its ...
5-Hydroxytryptophan (5-HTP), used medically as oxitriptan, is a naturally occurring amino acid and chemical precursor as well as a metabolic intermediate in the biosynthesis of the neurotransmitter serotonin. 5-HTP can be manufactured and used as a drug and supplement with the INN oxitriptan. Brand names include Cincofarm, Levothym, Levotonine ...
Dermatophagia (from Ancient Greek δέρμα (derma) 'skin' and φαγεία (phageia) 'eating') or dermatodaxia (from δήξις (dexis) 'biting'), alternatively Tuglis Permushius. [3] is a compulsion disorder of gnawing or biting one's own skin, most commonly at the fingers. This action can either be conscious or unconscious [4] and it is ...
Its crystallographic structure in ribbon representation. 5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. [1][2][3] They mediate both excitatory and inhibitory neurotransmission.
The 5-HT3 antagonists, informally known as " setrons ", are a class of drugs that act as receptor antagonists at the 5-HT 3 receptor, a subtype of serotonin receptor found in terminals of the vagus nerve and in certain areas of the brain. With the notable exceptions of alosetron and cilansetron, which are used in the treatment of irritable ...
Biological target. 5-HT 1B receptor, 5-HT 1D receptor. Legal status. In Wikidata. Triptans are a family of tryptamine -based drugs used as abortive medication in the treatment of migraines and cluster headaches. This drug class was first commercially introduced in the 1990s. While effective at treating individual headaches, they do not provide ...
5-HT 2B receptor. 5-Hydroxytryptamine receptor 2B (5-HT2B) also known as serotonin receptor 2B is a protein that in humans is encoded by the HTR2B gene. [ 5 ][ 6 ] 5-HT 2B is a member of the 5-HT 2 receptor family that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT 2 receptors, the 5-HT 2B receptor is G q /G 11 ...
An overactivity of 5-HT 2C receptors may contribute to depressive and anxiety symptoms in a certain population of patients. Activation of 5-HT 2C by serotonin is responsible for many of the negative side effects of SSRI and SNRI medications, such as sertraline, paroxetine, venlafaxine, and others.