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Specific activity (symbol a) is the activity per unit mass of a radionuclide and is a physical property of that radionuclide. [1] [2] It is usually given in units of becquerel per kilogram (Bq/kg), but another commonly used unit of specific activity is the curie per gram (Ci/g).
Radionuclides can be used to monitor processes such as DNA replication or amino acid transport. in physics and biology radionuclide X-ray fluorescence spectrometry is used to determine chemical composition of the compound. Radiation from a radionuclide source hits the sample and excites characteristic X-rays in the sample. This radiation is ...
RNT contrasts with sealed-source therapy (brachytherapy) where the radionuclide remains in a capsule or metal wire during treatment and needs to be physically placed precisely at the treatment position. [4] When the radionuclides are ligands (such as with Lutathera and Pluvicto), the technique is also known as radioligand therapy. [5]
This is contained in a certain volume, depending on the radioactive concentration, such as 5 to 10 mCi/mL (185 to 370 TBq/m 3); typical volumes include 50 or 25 μL. Not all molecules in the solution have a P-32 on the last (i.e., gamma) phosphate: the "specific activity" gives the radioactivity concentration and depends on the radionuclei's ...
Some radionuclides, such as cobalt-60 and iridium-192, are made by the neutron irradiation of normal non-radioactive cobalt and iridium metal in a nuclear reactor, creating radioactive nuclides of these elements which contain extra neutrons, compared to the original stable nuclides. In addition to their uses in radiography, both cobalt-60 (60 Co
The enzyme encoded by this gene is a member of the RAD51 protein family which assists in repair of DNA double strand breaks. RAD51 family members are homologous to the bacterial RecA, Archaeal RadA, and yeast Rad51. [4] [5] The protein is highly conserved in most eukaryotes, from yeast to humans. [6] The name RAD51 derives from RADiation ...
In other cases, imaging can be performed by labelling a suitable radionuclide to the same peptide as used for therapy. [22] Radionuclides that can be used for imaging include gallium-68, technetium-99m and fluorine-18. [21] Currently used peptides can result in high kidney doses, as the radiopharmaceutical is retained for relatively long ...
They are the primary source of radiogenic heating and radioactive decay products. Together, there are a total of 286 primordial nuclides. [a] The list then covers the ~700 radionuclides with half-lives longer than 1 hour, split into two tables, half-lives greater than one day and less than one day.