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A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
The phrase entourage effect was introduced in 1999. [9] [10] While originally identified as a novel method of endocannabinoid regulation by which multiple endogenous chemical species display a cooperative effect in eliciting a cellular response, the term has evolved to describe the polypharmacy effects of combined cannabis phytochemicals or whole plant extracts. [11]
The effects of Indica varieties are usually soothing and relaxing, with some strains inducing even sedative effects. Therefore, if you want a boost to be more active or creative, Sativa might be ...
The actions of Δ 9-THC result from its partial agonist activity at the cannabinoid receptor CB 1 (K i = 40.7 nM [23]), located mainly in the central nervous system, and the CB 2 receptor (K i = 36 nM [23]), mainly expressed in cells of the immune system. [24] The psychoactive effects of THC are primarily mediated by the activation of (mostly G ...
Cannabis plants vary widely, with different strains producing dynamic balances of cannabinoids (THC, CBD, etc.) and yielding markedly different effects. Popular strains are often hybrids of C. sativa and C. indica. The medicinal effects of cannabis are widely studied, and are active topics of research both at universities and private research ...
The long-term effects of cannabis have been the subject of ongoing debate. Given that the use of cannabis is illegal in most countries , clinical research presents a challenge and there is limited evidence from which to draw conclusions. [ 1 ]
Typically, adverse effects of medical cannabis use are not serious; [6] they include tiredness, dizziness, increased appetite, and cardiovascular and psychoactive effects. Other effects can include impaired short-term memory; impaired motor coordination; altered judgment; and paranoia or psychosis at high doses. [44]