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Pleomorphic adenomas may recur after a very long time from primary surgery, on average over 7–10 years and up to 24 years. [10] [11] Survival rates due to malignancy depends on the patient and extent of disease. [4] A 10-year survival ranges from 32-83%. [4] Of all cancers, salivary gland tumors account for only 1%. [4]
Relative incidence of parotid tumors, with Warthin's tumor near top right. [4] The gland most likely affected is the parotid gland. In fact, it is the only tumor virtually restricted to the parotid gland. Warthin's tumor is the second most common benign parotid tumor after pleomorphic adenoma, but its prevalence is steadily increasing. [5]
[3] [18] Saku et al. in 1997 [19] and Venturi [20] [21] in 2021, reported the causal role for ionizing radiation in salivary gland tumorigenesis, particularly for mucoepidermoid carcinoma. In the United States, salivary gland cancers are uncommon with an incidence rate of 1.7 in 100000 between 2009 and 2013. [22]
Pleomorphic adenoma (or benign mixed tumor) is a common benign salivary gland neoplasm characterised by neoplastic proliferation of epithelial (ductal) cells along with myoepithelial components, having a malignant potentiality. It is the most common type of salivary gland tumor and the most common tumor of the parotid gland.
Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases. Often appears pseudoencapsulated.
Parotid swelling can be an uncommon symptom of extrapulmonary tuberculosis (TB outside of the lungs). The usual symptoms are a cough, fever, weight loss, shortness of breath, chest pain, tiredness and chills. This is caused by the bacteria Mycobacterium tuberculosis. TB can also affect the heart, thyroid and adrenal glands but the main site of ...
Pneumoparotitis (also termed pneumosialadenitis [1] wind parotitis, [1] surgical mumps, [2] or anaesthesia mumps), [2] is a rare cause of parotid gland swelling which occurs when air is forced through the parotid (Stensen) duct resulting in inflation of the duct. [3]
Chronic sclerosing sialadenitis is a chronic (long-lasting) inflammatory condition affecting the salivary gland. Relatively rare in occurrence, this condition is benign, but presents as hard, indurated and enlarged masses that are clinically indistinguishable from salivary gland neoplasms or tumors.