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In vitro, CBG has identified pharmacodynamic actions and its mechanism of action appears to be from interactions with multiple targets. [1] [2] [3]CBG is a weak ligand of the cannabinoid CB 1 and CB 2 receptors with affinities (K i) of 380–2,600 nM and 153–3,460 nM, respectively.
Cannabis (/ ˈ k æ n ə b ɪ s / ⓘ) [2] is a genus of flowering plants in the family Cannabaceae that is widely accepted as being indigenous to and originating from the continent of Asia. [3] [4] [5] However, the number of species is disputed, with as many as three species being recognized: Cannabis sativa, C. indica, and C. ruderalis.
Cannabis is the most widely used illicit drug in the Western world. [3] In the United States, 10-20% of those who begin the use of cannabis daily will later become dependent. [4] [5] In 2007 there was an estimated 143 - 190 million cannabis users around the world, making cannabis the most used and illicit drug in the world. [6]
Cannabis plants can exhibit wide variation in the quantity and type of cannabinoids they produce. The mixture of cannabinoids produced by a plant is known as the plant's cannabinoid profile. Selective breeding has been used to control the genetics of plants and modify the cannabinoid profile.
This is an accepted version of this page This is the latest accepted revision, reviewed on 22 February 2025. Number referring to cannabis 420 originally "4:20 Louis" Statue of Louis Pasteur at San Rafael High School, by Benny Bufano (1940), site of the earliest 4:20 gatherings in 1971 Observed by Cannabis counterculture, legal reformers, entheogenic spiritualists, and general users of cannabis ...
Cannabis strains is a popular name to refer to plant varieties of the monospecific genus Cannabis sativa L.. They are either pure or hybrid varieties of the plant, which encompasses various sub-species C. sativa , C. indica , and C. ruderalis .
Cultural figureheads such as Bob Marley popularized Rastafari and ganja through reggae music. In 1976, Peter Tosh defended the use of ganja in the song "Legalize It". [14] The hip hop group Cypress Hill revived the term in the United States in 2004 in a song titled "Ganja Bus", followed by other artists, including rapper Eminem, in the 2009 song "Must Be the Ganja".
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.