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Additional researched vinca alkaloids include vincaminol, vineridine, and vinburnine. Vinpocetine is a semi-synthetic derivative of vincamine (sometimes described as "a synthetic ethyl ester of apovincamine"). [14] Minor vinca alkaloids include minovincine, methoxyminovincine, minovincinine, vincadifformine, desoxyvincaminol, and vincamajine ...
It is a source of the drugs vincristine and vinblastine, used to treat cancer. [3] It was formerly included in the genus Vinca as Vinca rosea. It has many vernacular names among which are arivotaombelona or rivotambelona, tonga, tongatse or trongatse, tsimatiririnina, and vonenina. [4]
Serratiopeptidase (Serratia E-15 protease, also known as serralysin, serrapeptase, serratiapeptase, serratia peptidase, serratio peptidase, or serrapeptidase) is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp. E-15, now known as Serratia marcescens ATCC 21074. [1]
Vinca difformis in habitat, Cáceres, Spain. Vinca plants are subshrubs or herbaceous, and have slender trailing stems 1–2 m (3 + 1 ⁄ 2 – 6 + 1 ⁄ 2 ft) long but not growing more than 20–70 cm (8– 27 + 1 ⁄ 2 in) above ground; the stems frequently take root where they touch the ground, enabling the plant to spread widely.
They were isolated from extracts leaves of the Catharanthus roseus (Vinca rosea) plant at the University of Western Ontario in 1958. [5] First drug belong to the taxanes and paclitaxel , discovered in extracts from the bark of the yew tree, Taxus brevifolia , in 1967 by Monroe Wall and Mansukh Wani but, its tubulin inhibition activity was not ...
Mutations in the gene lead to hyperuricemia.At least 67 disease-causing mutations in this gene have been discovered: [5] Some men have partial (up to 20% less activity of the enzyme) HGPRT deficiency that causes high levels of uric acid in the blood, which leads to the development of gouty arthritis and the formation of uric acid stones in the urinary tract.
Rosavin (also known as rosin, rosavin, and rosarin) are a family of cinnamyl mono- and diglycosides that are key ingredients of Rhodiola rosea L., (R. rosea). R. rosea is an important medicinal plant commonly used throughout Europe, Asia, and North America, that has been recognized as a botanical adaptogen by the European Medicines Agency. [1]
Enzyme replacement therapy is available to treat mainly Fabry disease and Gaucher disease, and people with these types of sphingolipidoses may live well into adulthood. The other types are generally fatal by age 1 to 5 years for infantile forms, but progression may be mild for juvenile- or adult-onset forms.
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