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  2. MACI: Repairing knee cartilage damage - Mayo Clinic Orthopedics...

    sportsmedicine.mayoclinic.org/news/maci-repairing-knee-cartilage-damage

    ANSWER: The new technique is called matrix-associated autologous chondrocyte implantation, or MACI. It can be effective for repairing isolated cartilage damage in the knee, but it’s not useful for people whose knee cartilage is diffusely damaged due to arthritis.

  3. Knee Cartilage Replacement: 5 Options to Consider - Healthline

    www.healthline.com/.../knee-pain-treatment/knee-cartilage-replacement

    Advances in orthopedic medicine provide many options for treating knee injuries. Some long-standing approaches include surgery to repair torn cartilage or knee joint replacement.

  4. Mayo Clinic offers unique regenerative medicine procedure for ...

    www.mayoclinic.org/medical-professionals/orthopedic-surgery/news/mayo-clinic...

    RECLAIM is a one-stage innovative procedure for hip and knee that enables tissue growth and restoration of cartilage in the patient's joint. Within one year, the defect is filled. DNA analysis has shown this to be patient-derived new cartilage tissue without donor DNA remaining.

  5. Knee Cartilage Repair, Regeneration, and Replacement

    www.sports-health.com/treatment/knee-injury-treatment/knee-cartilage-repair...

    There are three common knee cartilage regeneration techniques that use bleeding to spur cartilage healing: Knee microfracture, which requires the damaged cartilage to be cleared away completely. The surgeon then uses a sharpened tool called an awl to pierce the bone.

  6. Causes and Treatment Options for No Cartilage in the Knee -...

    www.verywellhealth.com/treatments-for-loss-of-cartilage-in-knee-5096944

    Knee arthroscopy is the most common type of surgical procedure performed to repair, remove, or replace damaged cartilage in the knee joint that can cause pain and limit the range of motion of the knee joint.

  7. Articular Cartilage Restoration - OrthoInfo - AAOS

    orthoinfo.aaos.org/en/treatment/articular-cartilage-restoration

    The knee is the most common area for cartilage restoration. Ankle, shoulder, and elbow problems may also be treated. Articular cartilage in the knee damaged in a single, or focal, location.

  8. Novel stem cell therapy for repair of knee cartilage - Mayo...

    www.mayoclinic.org/medical-professionals/orthopedic-surgery/news/novel-stem...

    A unique approach to repairing knee cartilage mixes donor mesenchymal stem cells from the Mayo Clinic Center for Regenerative Medicine stem cell bank with recycled autologous cells to quickly obtain enough cells to fill the patient's cartilage defect without operating twice.

  9. Using regenerative medicine to treat knee pain

    sportsmedicine.mayoclinic.org/news/using-regenerative-medicine-to-treat-knee-pain

    When knee cartilage is damaged, treatment options are available, including a new method using a patient’s own cells to grow new cartilage. The new technique is called matrix-associated autologous chondrocyte implantation, or MACI.

  10. Knee Cartilage Restoration Rockford | Knee Cartilage Damage...

    www.vanthielmd.com/knee-cartilage-restoration-orthopedic-surgeon-elgin...

    Dr Van Thiel, an orthopedic surgeon in Elgin, Rockford and Crystal Lake, IL offers knee cartilage restoration to repair damaged articular cartilage in the knee joint.

  11. Knee Cartilage Restoration Chicago, Illinois | Damaged Articular...

    www.jonwhitehurstmd.com/knee-cartilage-restoration-orthopedic-surgeon-rockford...

    Knee cartilage restoration is a surgical technique to repair damaged articular cartilage in the knee joint by stimulating new growth of cartilage or by transplanting cartilage into areas with defects in order to relieve pain and restore normal function to the knee.

  12. Knee Cartilage Clinic - Mayo Clinic Orthopedics & Sports Medicine

    sportsmedicine.mayoclinic.org/specialtyclinic/knee-cartilage-clinic

    Knee cartilage repair. Knee pain due to meniscus or cartilage damage. Leg alignment issues (malalignment) Knee preservation after previous injury, such as ACL tears, osteochondritis dissecans, or patella instability. Make an appointment at one of our locations below to see one of our specialists.

  13. Knee replacement - Mayo Clinic

    www.mayoclinic.org/tests-procedures/knee-replacement/about/pac-20385276

    Knee replacement surgery replaces parts of injured or worn-out knee joints. The surgery can help ease pain and make the knee work better. During the surgery, damaged bone and cartilage are replaced with parts made of metal and plastic.

  14. Mayo Clinic Q and A: New technique for repairing knee cartilage...

    newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-new-technique-for...

    ANSWER: The new technique is called matrix-associated autologous chondrocyte implantation, or MACI. It can be effective for repairing isolated cartilage damage in the knee, but it's not useful for people whose knee cartilage is diffusely damaged due to arthritis.

  15. Cartilage Replacement as a Treatment for Knee Arthritis -...

    www.verywellhealth.com/cartilage-replacement-2549499

    By Jonathan Cluett, MD. Updated on June 07, 2022. Medically reviewed by Oluseun Olufade, MD. Print. Table of Contents. Knee Arthritis. Replacing Worn Cartilage Issues. Growing Cartilage in the Lab. Cartilage Replacement. Knee arthritis is a condition that causes damage to our joints and the cartilage that helps the knees to function normally.

  16. Cartilage Injury and Repair > Fact Sheets - Yale Medicine

    www.yalemedicine.org/conditions/cartilage-injury-and-repair

    When the articular cartilage is damaged, surgical procedures can effectively repair and restore the tissue. In general, healthy individuals younger than 40 with minor articular cartilage injuries have the best outcomes and often successfully return to pre-injury activities.

  17. Latest Advances in Cartilage Repair and Regeneration - HSS

    www.hss.edu/condition-list_cartilage-repair.asp

    In its simplest terms, cartilage repair (regeneration) surgery results in the formation of robust cartilage-like tissue around the joint where the cartilage has worn away or been damaged. Cartilage regeneration typically requires some sort of surgical intervention.

  18. Total Knee Replacement - Ortho Illinois

    www.orthoillinois.com/knee/total-knee-replacement

    Pneumonia. Blood Clots. Reaction to anesthesia. Blood vessel or nerve injury. Kneecap dislocation. Implant wear or loosening. Total knee replacement is a successful surgery to remove all or most knee pain due to arthritis. Some patients may continue to feel kneecap pain when kneeling after surgery. Most total knee replacements last 15-20 years.

  19. Torn Cartilage in the Knee Symptoms and Treatment - Verywell...

    www.verywellhealth.com/difference-between-meniscus-tear-and-cartilage-tear-2549642

    Knee cartilage tears can be caused by injury, arthritis, or chronic overuse. Not all knee cartilage tears require surgery, but there are certain tears that will heal a lot better if they are fixed surgically.

  20. Knee Cartilage Replacement | Symptoms, treatment, recovery -...

    www.sportsmd.com/sports-injuries/knee-injuries/knee-cartilage-replacement

    Each year, hundreds of thousands of Americans undergo surgery to repair torn knee cartilage. “Repair” usually means shaving damaged cartilage. But some younger, healthier patients are trying cartilage replacement, a more experimental therapy.

  21. One-Step Cartilage Repair of Full-Thickness Knee Chondral Lesions...

    journals.sagepub.com/doi/10.1177/03635465241287524

    To examine the long-term clinical outcomes, after a mean follow-up duration of 14 years, of cartilage repair in the knee using a hyaluronic acid–based scaffold in association with bone marrow aspirate concentrate (HA-BMAC) and to evaluate the effect of age, lesion characteristics, and associated treatments on the outcome of this cartilage ...

  22. Background: One-step cell-based techniques of cartilage repair that lead to restoration of durable chondral tissue and long-term maintenance of joint function are cost-effective and ideal for routine use. Purposes: To examine the long-term clinical outcomes, after a mean follow-up duration of 14 years, of cartilage repair in the knee using a hyaluronic acid-based scaffold in association with ...

  23. Knee Replacement Alternatives to Consider - Johns Hopkins...

    www.hopkinsmedicine.org/health/treatment-tests-and-therapies/knee-replacement...

    For knees with a limited amount of arthritis and good alignment of the bones, doctors may be able to offer newer treatments that replace cartilage instead of replacing the entire joint. There are several cartilage-regeneration techniques that you may consider and discuss with an orthopaedic surgeon.

  24. Exosomes derived from platelet-rich plasma present a novel...

    josr-online.biomedcentral.com/articles/10.1186/s13018-024-05202-z

    Background The aim of this study was to investigate the therapeutic effects and mechanisms of PRP-exos combined with cyclic peptide-modified β-TCP scaffold in the treatment of rabbit knee cartilage defect. Methods PRP-exos were extracted and characterized by TEM, NTA and WB. The therapeutic effects were evaluated by ICRS score, HE staining, Immunohistochemistry, qRT-PCR and ELISA. The repair ...

  25. From dysfunction to healing: advances in mitochondrial therapy...

    translational-medicine.biomedcentral.com/articles/10.1186/s12967-024-05799-z

    Osteoarthritis (OA) is a chronic degenerative joint condition characterised by cartilage deterioration and changes in bone morphology, resulting in pain and impaired joint mobility. Investigation into the pathophysiological mechanisms underlying OA has highlighted the significance of mitochondrial dysfunction in its progression. Mitochondria, which are cellular organelles, play a crucial role ...