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The Journal of Liposome Research is a peer-reviewed academic journal that publishes original research on the topics of liposomes and related systems, lipid-based delivery systems, lipid biology, and both synthetic and physical lipid chemistry.
The word liposome derives from two Greek words: lipo ("fat") and soma ("body"); it is so named because its composition is primarily of phospholipid.. Liposomes were first described by British hematologist Alec Douglas Bangham [10] [11] [12] in 1961 at the Babraham Institute, in Cambridge—findings that were published 1964.
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The use of cationic lipids helps to enhance the overall stability and efficiency of liposomes. Although cationic lipids themselves are able to encapsulate nucleic acids into liposomes, the transfection efficiency is low due to a process known as endosomal escape.
There is an interest in liposomal medicine because it features targeted drug delivery while mitigating the damage to healthy cells and tissues. [15] One of the combination products under liposome therapy that is being researched for cancer therapy applications is immunoliposome therapy. [15]
A typical micelle in water forms an aggregate with the hydrophilic "head" regions in contact with surrounding solvent, sequestering the hydrophobic single-tail regions in the micelle centre. This phase is caused by the packing behavior of single-tail lipids in a bilayer. The difficulty in filling the volume of the interior of a bilayer, while ...
Unilamellar liposomes are used to study biological systems and to mimic cell membranes, and are classified into three groups based on their size: small unilamellar liposomes/vesicles (SUVs) that with a size range of 20–100 nm, large unilamellar liposomes/vesicles (LUVs) with a size range of 100–1000 nm and giant unilamellar liposomes ...
The journal is international; it is managed by NIMS, which was joined in 2014 by the Swiss Federal Laboratories for Materials Science and Technology (Empa). [1] Currently STAM is an electronic journal, its articles are continuously published online. Its sister journal, STAM Methods, has been launched in 2021. [2]