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Temsirolimus is a specific inhibitor of mTOR and interferes with the synthesis of proteins that regulate proliferation, growth, and survival of tumor cells. Though temsirolimus shows activity on its own, it is also known to be converted to sirolimus (rapamycin) in vivo; [4] therefore, its activity may be more attributed to its metabolite rather than the prodrug itself (despite claims to the ...
2475 56717 Ensembl ENSG00000198793 ENSMUSG00000028991 UniProt P42345 Q9JLN9 RefSeq (mRNA) NM_004958 NM_001386500 NM_001386501 NM_020009 RefSeq (protein) NP_004949 NP_064393 Location (UCSC) Chr 1: 11.11 – 11.26 Mb Chr 4: 148.53 – 148.64 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The mammalian target of rapamycin (mTOR), also referred to as the mechanistic target of rapamycin ...
The scheme is one of a number developed by Biodiversity Information Standards particularly aimed at taxonomic databases. [2] The starting point was the "need for an agreed system of geographical units at approximately 'country' level and upwards for use in recording plant distributions". [1]
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In the reaction center of PSII of plants and cyanobacteria, the light energy is used to split water into oxygen, protons, and electrons. The protons will be used in proton pumping to fuel the ATP synthase at the end of an electron transport chain. A majority of the reactions occur at the D1 and D2 subunits of PSII.
Tillandsia is a genus of around 650 species of evergreen, perennial flowering plants in the family Bromeliaceae, native to the forests, mountains and deserts of the Neotropics, from northern Mexico and the southeastern United States to Mesoamerica and the Caribbean to central Argentina.