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Ecological plaque hypothesis and the aetiology of dental caries The ecological plaque hypothesis, a combination of the two previously mentioned hypotheses, suggests that there are certain species responsible for pathology, but are present in insufficient quantities to cause damage to a healthy individual. [ 13 ]
A caries vaccine is a vaccine to prevent and protect against tooth decay. [1] Streptococcus mutans ( S. mutans ) has been identified as the major etiological agent of human dental caries. The development of a vaccine for tooth decay has been under investigation since the 1970s.
Dental plaque is a biofilm that attaches to tooth surfaces, restorations and prosthetic appliances (including dentures and bridges) if left undisturbed.Understanding the formation, composition and characteristics of plaque helps in its control. [6]
Pericoronitis is inflammation of the soft tissues surrounding the crown of a partially erupted tooth, [1] including the gingiva (gums) and the dental follicle. [2] The soft tissue covering a partially erupted tooth is known as an operculum, an area which can be difficult to access with normal oral hygiene methods.
Dental caries is a dental biofilm-related oral disease associated with increased consumption of dietary sugar and fermentable carbohydrates. When dental biofilms remain on tooth surfaces, along with frequent exposure to sugars, acidogenic bacteria (members of dental biofilms) will metabolize the sugars to organic acids.
Dental caries result when the demineralization rate is faster than the remineralization, producing net mineral loss, which occurs when there is an ecologic shift within the dental biofilm from a balanced population of microorganisms to a population that produces acids and can survive in an acid environment.
Early childhood caries (ECC) is a multifactorial disease, with risk factors including but not limited to, cariogenic bacteria, diet practices and socioeconomic factors. [6] Deciduous teeth begin to erupt at 6 months of age, once visible in the oral cavity they are susceptible to tooth decay or dental caries. [1]
Main building of Vipeholm hospital, now a secondary school. The Vipeholm experiments or Vipeholm Study (Swedish: Vipeholmsexperimenten) were a series of human experiments where patients of Vipeholm Hospital for the intellectually disabled in Lund, Sweden, were fed large amounts of sweets, including "extra sticky toffee" [clarification needed] to provoke dental caries.