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The main efficacy measurement was the time to death from cardiovascular causes or need to be hospitalized for heart failure. [33] Of the individuals who received empagliflozin for an average of about two years, 14% died from cardiovascular causes or were hospitalized for heart failure, compared to 17% of the participants who received the ...
In a statement on Friday, the two partners said Jardiance cut the risk of kidney disease progression and cardiovascular death by 28%, citing results from a late-stage trial which included people ...
Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors.
Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment
Balkan endemic nephropathy [1] (BEN) is a form of interstitial nephritis causing kidney failure.It was first identified in the 1920s among several small, discrete communities along the Danube River and its major tributaries, in the modern countries of Croatia, Bosnia and Herzegovina, Serbia, Kosovo, Romania, and Bulgaria.
Onchocerciasis (river blindness) is the world's second leading cause of infectious blindness. It is caused by the nematode Onchocerca volvulus, which is transmitted to people via the bite of a black fly. The current WHO goal is to increase the number of countries free of transmission from 4 (in 2020) to 12 in 2030. [110]
Half of the hospital beds occupied in the world are related to the lack of safe drinking water. Unsafe water leads to the 88% of the global cases of diarrhea and 90% of the deaths of diarreaheal diseases in children under five years old. Most of these deaths occur in developing countries due to poverty and the high cost of safe water. [13]
The leading cause of death for both men and women in the United States is heart disease. [34] In Canada, heart disease is the second leading cause of death. In 2014, it was the cause of death for 51,000 people. [35] In Australia, heart disease is also the leading cause of death. 29% of deaths in 2015, had an underlying cause of heart disease. [36]
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