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Maternal serum AFP (MSAFP) varies by orders of magnitude during the course of a normal pregnancy. MSAFP increases rapidly until about 32 weeks gestation, then decreases gradually. After the pregnancy ends it decreases rapidly, with a half-life of about 5 days. Typically, MSAFP is measured in the beginning of the second trimester (14–16 weeks).
Having multiple gestations, such as twins, increases MSAFP because each fetus secretes its own AFP Incorrect estimation of gestational age is the most common cause of abnormal MSAFP levels An example of an algorithm for indications for further testing depending on the outcome of non-genetic blood tests including the triple test.
174 11576 Ensembl ENSG00000081051 ENSMUSG00000054932 UniProt P02771 P02772 RefSeq (mRNA) NM_001134 NM_001354717 NM_007423 RefSeq (protein) NP_001125 NP_001341646 NP_031449 Location (UCSC) Chr 4: 73.43 – 73.46 Mb Chr 5: 90.64 – 90.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Alpha-fetoprotein (AFP, α-fetoprotein ; also sometimes called alpha-1-fetoprotein, alpha ...
A multiple of the median (MoM) is a measure of how far an individual test result deviates from the median.MoM is commonly used to report the results of medical screening tests, particularly where the results of the individual tests are highly variable.
An elevated MSAFP measured at 16–18 weeks gestation is a good predictor of open neural tube defects, however the test has a very high false positive rate, (2% of all women tested in Ontario, Canada between 1993 and 2000 tested positive without having an open neural tube defect, although 5% is the commonly quoted result worldwide) and only a ...
The Sample and Data Relationship Format (SDRF) is part of the MAGE-TAB standard for communicating the results of microarray investigations, including all information required for MIAME compliance. [ 1 ]
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Page:Analysis and Assessment of Gateway Process.pdf/27 Metadata This file contains additional information, probably added from the digital camera or scanner used to create or digitize it.
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