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A classic example of a syncytium is the formation of skeletal muscle.Large skeletal muscle fibers form by the fusion of thousands of individual muscle cells. The multinucleated arrangement is important in pathologic states such as myopathy, where focal necrosis (death) of a portion of a skeletal muscle fiber does not result in necrosis of the adjacent sections of that same skeletal muscle ...
Muscle cells develop from embryonic precursor cells called myoblasts. [1] Skeletal muscle cells form by fusion of myoblasts to produce multinucleated cells in a process known as myogenesis. [4] [5] Skeletal muscle cells and cardiac muscle cells both contain myofibrils and sarcomeres and form a striated muscle tissue. [6]
Myogenesis is the formation of skeletal muscular tissue, particularly during embryonic development. Myoblasts (cells with a single nucleus, represented in violet) fusing together to form muscle fibers (multinucleated muscle cells) during myogenesis
Skeletal muscle tissue consists of elongated, multinucleate muscle cells called muscle fibers, and is responsible for movements of the body. Other tissues in skeletal muscle include tendons and perimysium . [ 3 ]
The tissue of a skeletal muscle is striated – having a striped appearance due to the arrangement of the sarcomeres. A skeletal muscle contains multiple fascicles – bundles of muscle fibers. Each individual fiber, and each muscle is surrounded by a type of connective tissue layer of fascia. Muscle fibers are formed from the fusion of ...
Multinucleate cells (also known as multinucleated cells or polynuclear cells) are eukaryotic cells that have more than one nucleus, i.e., multiple nuclei share one common cytoplasm. Mitosis in multinucleate cells can occur either in a coordinated, synchronous manner where all nuclei divide simultaneously or asynchronously where individual ...
Smooth muscle-containing tissue needs to be stretched often, so elasticity is an important attribute of smooth muscle. Smooth muscle cells may secrete a complex extracellular matrix containing collagen (predominantly types I and III), elastin, glycoproteins, and proteoglycans. Smooth muscle also has specific elastin and collagen receptors to ...
Cell fusion is an important cellular process in which several uninucleate cells (cells with a single nucleus) combine to form a multinucleate cell, known as a syncytium.Cell fusion occurs during differentiation of myoblasts, osteoclasts and trophoblasts, during embryogenesis, and morphogenesis. [1]