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Schematic drawing of a Herpesviridae virion. All members of the Herpesviridae share a common structure; a relatively large, monopartite, double-stranded, linear DNA genome encoding 100–200 genes encased within an icosahedral protein cage (with T=16 symmetry) called the capsid, which is itself wrapped in a protein layer called the tegument containing both viral proteins and viral mRNAs and a ...
Human herpesvirus 6 (HHV-6) is the common collective name for human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B). These closely related viruses are two of the nine known herpesviruses that have humans as their primary host. [1]
The herpesvirus was first isolated from the blue wildebeest in 1960 by veterinary scientist Walter Plowright. [4] The genus Herpesvirus was established in 1971 in the first report of the International Committee on Taxonomy of Viruses (ICTV). This genus consisted of 23 viruses and 4 groups of viruses.
Herpes virus DNA contains a gene for a protein called ICP4, which is an important transactivator of genes associated with lytic infection in HSV-1. [47] Elements surrounding the gene for ICP4 bind a protein known as the human neuronal protein neuronal restrictive silencing factor (NRSF) or human repressor element silencing transcription factor ...
Herpes virus may refer to: Any member of the large family of DNA viruses known as Herpesviridae. Human herpesviruses, nine types of herpesviruses that can cause diseases in humans Herpes simplex virus 1 and 2, responsible for herpes simplex infections; Human alphaherpesvirus 3, also called varicella-zoster virus, responsible for chickenpox and ...
Herpes simplex, often known simply as herpes, is a viral infection caused by the herpes simplex virus. [5] Herpes infections are categorized by the area of the body that is infected.
Human cytomegalovirus (HCMV), also called human herpesvirus 5 (HHV-5), is a species of virus in the genus Cytomegalovirus, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is also commonly called CMV. [3]
Human herpesvirus 6B affects humans. Primary infection with this virus is the cause of the common childhood illness exanthema subitum (also known as roseola infantum or sixth disease). Additionally, reactivation is common in transplant recipients, which can cause several clinical manifestations such as encephalitis , bone marrow suppression ...