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Schematic representation of transmembrane proteins: 1) a single-pass membrane protein 2) a multipass membrane protein (α-helix) 3) a multipass membrane protein β-sheet. The membrane is represented in light yellow. A transmembrane protein is a type of integral membrane protein that spans the entirety of the cell membrane.
A transmembrane domain (TMD) is a membrane-spanning protein domain.TMDs may consist of one or several alpha-helices or a transmembrane beta barrel.Because the interior of the lipid bilayer is hydrophobic, the amino acid residues in TMDs are often hydrophobic, although proteins such as membrane pumps and ion channels can contain polar residues.
Transmembrane channel-like protein 1 is a protein that in humans is encoded by the TMC1 gene. [5] [6] [7] TMC1 contains six transmembrane domains with both the C and N termini on the endoplasmic side of the membrane, as well as a large loop between domains 4 and 5.
A membrane transport protein is a membrane protein involved in the movement of ions, small molecules, and macromolecules, such as another protein, across a biological membrane. Transport proteins are integral transmembrane proteins ; that is they exist permanently within and span the membrane across which they transport substances.
TMEM19 is a protein spanning 336 amino acids. It has 6 transmembrane regions. The protein is found at moderate levels in the body, with the highest expression found in superior cervical ganglia and cardiac myocytes. [10] TMEM19 interacts with many proteins, most of these proteins are localized around membranes found in the cell.
Transmembrane protein 61 (TMEM61) is a protein that is encoded by the TMEM61 gene in humans.It is located on the first chromosome in humans [5] and is highly expressed in the intestinal regions predominantly the kidney, adrenal gland and pituitary tissues. [6]
TMEM128, also known as Transmembrane Protein 128, is a protein that in humans is encoded by the TMEM128 gene. TMEM128 has three variants, varying in 5' UTR 's and start codon location. [ 5 ] TMEM128 contains four transmembrane domains and is localized in the Endoplasmic Reticulum membrane.
TMEM44 (Transmembrane protein 44) is a protein that in humans is encoded by the TMEM44 gene. [5] DKFZp686O18124 is a synonym of TMEM44. Gene.
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