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One of the fundamental problems with pellets, however, is that they deliver a supratherapeutic, or higher than usual, dose (often around 200 to 400 nanograms per deciliter; normal levels in men ...
Levonorgestrel-releasing implant is implanted under the skin in the upper arm of a woman, by creating a small incision and inserting the capsules in a fanlike shape. Insertion usually takes 15 minutes and the capsules can sometimes be seen under the skin, although usually they look like small veins. They can also be felt under the skin.
Progesterone is a hormone in the endometrium that counteracts estrogen driven growth. [67] Very low levels of progesterone will cause estrogen to act more, leading to endometrial hyperplasia and adenocarcinoma. [67] These effects can be minimized if treated with progestin, but not in very many cases.
Leuprorelin is in the gonadotropin-releasing hormone (GnRH) analogue family of medications. [10] It works by decreasing gonadotropins and therefore decreasing testosterone and estradiol. [10] Common side effects include hot flashes, unstable mood, trouble sleeping, headaches, and pain at the site of injection. [10]
Little is known about the long-term side effects of hormone or puberty blockers in children with gender dysphoria. Although puberty blockers are known to be safe and physically reversible treatment if stopped in the short term, it is also not known whether hormone blockers affect the development of factors like bone mineral density, brain ...
Bioidentical hormones fit precisely into human hormone receptors while conventional hormones fit "cockeyed"; this mismatch causes serious side effects Synthetic progestins and endogenous progesterone have different binding affinities for different receptors, depending on the model and animal used; these differing pharmacodynamics have not been ...
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