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The main metabolite in humans, which is pharmacologically inactive [7] [22] The route of administration has only a slight effect on the drug's concentrations in the bloodstream: when given as an intramuscular injection , its bioavailability is 90% (as compared to the 100% availability when given directly into a vein), and its highest ...
[14] [15] [16] A dose of 5,000 Gy is estimated to introduce several hundred double-strand breaks (DSBs) into the organism's DNA (~0.005 DSB/Gy/Mbp (haploid genome)). For comparison, a chest X-ray or Apollo mission involves about 1 mGy, 5 Gy can kill a human, 200–800 Gy will kill E. coli , and more than 4,000 Gy will kill the radiation ...
Carbofuran is a carbamate insecticide, banned in the US, the EU and Canada but still widely used in South America, Australia and Asia. [6] It is a systemic insecticide, which means that the plant absorbs it through the roots, and from there the plant distributes it throughout its organs where insecticidal concentrations are attained.
The definition was refined in 1950 as "that dose of any ionizing radiation which produces a relevant biological effect equal to that produced by one roentgen of high-voltage x-radiation." [19] Using data available at the time, the rem was variously evaluated as 83, 93, or 95 erg/gram. [20]
[9] [10] Overdose of only a small number of capsules can be fatal. [10] Chewing or sucking on the capsule, releasing the drug into the mouth, can also lead to laryngospasm, bronchospasm, and circulatory collapse. [7] It is unclear if use in pregnancy or breastfeeding is safe. [11] Benzonatate is a local anesthetic and voltage-gated sodium ...
Spirulina is the dried biomass of cyanobacteria (blue-green algae) that can be consumed by humans and animals. The three species are Arthrospira platensis, A. fusiformis, and A. maxima. Cultivated worldwide, Arthrospira is used as a dietary supplement or whole food. [1]
For many individuals, doses above three grams may be overwhelming. For a few rare people, doses as small as 0.25 gram can produce full-blown effects normally associated with very high doses. For most people, however, that dose level would have virtually no effects. There are many different ways to ingest Psilocybe cubensis. Users may prefer to ...
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin–norepinephrine reuptake inhibitor (SNRI) class. [6] [9] It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. [9]