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The Bohr equation, named after Danish physician Christian Bohr (1855–1911), describes the amount of physiological dead space in a person's lungs. This is given as a ratio of dead space to tidal volume. It differs from anatomical dead space as measured by Fowler's method as it includes alveolar dead space.
Mechanical dead space or external dead space is volume in the passages of a breathing apparatus in which the breathing gas flows in both directions as the user breathes in and out, causing the last exhaled gas to be immediately inhaled on the next breath, increasing the necessary tidal volume and respiratory effort to get the same amount of ...
The Shunt equation (also known as the Berggren equation) quantifies the extent to which venous blood bypasses oxygenation in the capillaries of the lung.. “Shunt” and “dead space“ are terms used to describe conditions where either blood flow or ventilation do not interact with each other in the lung, as they should for efficient gas exchange to take place.
The healthy human body will alter minute volume in an attempt to maintain physiologic homeostasis. A normal minute volume while resting is about 5–8 liters per minute in humans. [1] Minute volume generally decreases when at rest, and increases with exercise. For example, during light activities minute volume may be around 12 litres.
In medicine, the ratio of physiologic dead space over tidal volume (V D /V T) is a routine measurement, expressing the ratio of dead-space ventilation (V D) to tidal ventilation (V T), as in physiologic research or the care of patients with respiratory disease. [1]
In respiratory physiology, the ventilation/perfusion ratio (V/Q ratio) is a ratio used to assess the efficiency and adequacy of the ventilation-perfusion coupling and thus the matching of two variables: V – ventilation – the air that reaches the alveoli; Q – perfusion – the blood that reaches the alveoli via the capillaries
The dead space can be determined from this curve by drawing a vertical line down the curve such that the areas below the curve (left of the line) and above the curve (right of the line) are equal. Most people with a normal distribution of airways resistances will reduce their expired end-tidal nitrogen concentrations to less than 2.5% within ...
In the early 1900s, Christian Bohr was a professor at the University of Copenhagen in Denmark, already well known for his work in the field of respiratory physiology. [3] He had spent the last two decades studying the solubility of oxygen, carbon dioxide, and other gases in various liquids, [ 4 ] and had conducted extensive research on ...