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Lugol's iodine is a liquid made up of two parts potassium iodide for every one part elemental iodine in water. [8] Lugol's iodine was first made in 1829 by the French physician Jean Lugol. [7] [8] It is on the World Health Organization's List of Essential Medicines. [9] [10] Lugol's iodine is available as a generic medication and over the ...
The composition of Schiller's iodine is the same as Lugol's iodine, the latter being more concentrated. When Schiller's iodine is not available, Lugol's iodine can be used as an alternative. Schiller's test is not specific for cervical cancer, as areas of inflammation, ulceration and keratosis may also not take up the stain. [2]
Tincture of iodine: iodine in ethanol, or iodine and sodium iodide in a mixture of ethanol and water. Lugol's iodine: iodine and iodide in water alone, forming mostly triiodide. Unlike tincture of iodine, Lugol's iodine has a minimised amount of the free iodine (I 2) component. Iodine glycerin, a preparation used in dentistry.
Nevertheless, the iodide in tincture of iodine used as a water disinfectant does supply more than adequate nutritional iodine, perhaps 30 or more times the recommended daily allowance per liter or quart. Application of tincture or Lugol's to the skin also results in absorption and bioavailability of some moderate fraction of the iodine.
Guidelines recommend the administration of inorganic iodide (potassium iodide or Lugol's iodine [6] [21]) to reduce the synthesis and release of thyroid hormone. In high dosage, iodine may reduce the synthesis of thyroid hormone via the Wolff–Chaikoff effect and its release via the Plummer effect. [5]
Wrong timing of iodine use may even increase the risk by triggering the Plummer effect. [10] The Plummer effect is, however, helpful in the management of thyrotoxicosis, where the usage of Lugol’s solution helps to limit the release of thyroid hormones into the bloodstream. [4]
Iodine deficiency is a lack of the trace element iodine, an essential nutrient in the diet.It may result in metabolic problems such as goiter, sometimes as an endemic goiter as well as congenital iodine deficiency syndrome due to untreated congenital hypothyroidism, which results in developmental delays and other health problems.
Hemiamyloidity in mycology refers to a special case of cell wall amyloidity where the blue staining by iodine only occurs when the tissue was pretreated with potassium hydroxide solution (KOH) or other strong bases, whereas direct application of iodine causes a red reaction when using Lugol's solution, but no reaction when using Melzer's reagent.
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