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An antiarthritic is any drug used to relieve or prevent arthritic symptoms, such as joint pain or joint stiffness. Depending on the antiarthritic drug class, it is used for managing pain, reducing inflammation or acting as an immunosuppressant. These drugs are typically given orally, topically or through administration by injection.
Several approved drugs are being investigated as repurposed agents in the treatment of osteoarthritis such as liraglutide (anti-diabetic and anti-obesity drug: NCT02905864), Metformin (anti-diabetic drug: NCT04767841, NCT05034029), Zoledronic acid (anti-osteoporotic drug: NCT04303026), etc. [4] Paroxetine has been deemed to have DMOAD activity ...
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old. Side effects may include liver problems. [1]
Gastric adverse effects may be reduced by taking medications that suppress acid production such as proton pump inhibitors (e.g.: omeprazole and esomeprazole), or by treatment with a drug that mimics prostaglandin in order to restore the lining of the GI tract (e.g.: a prostaglandin analog misoprostol). [40]
Diacerein , also known as diacetylrhein, is a slow-acting medicine of the class anthraquinone used to treat joint diseases such as osteoarthritis (swelling and pain in the joints). [1] It works by inhibiting interleukin-1 beta .
The U.S. Food and Drug Administration announced late Thursday it has approved expanding the use of Eli Lilly's (LLY) blockbuster antidepressant Cymbalta to treat chronic musculoskeletal pain, such ...
The pain medication paracetamol (acetaminophen) is the first line treatment for osteoarthritis. [ 61 ] [ 94 ] Pain relief does not differ according to dosage. [ 62 ] However, a 2015 review found acetaminophen to have only a small short-term benefit with some concerns on abnormal results for liver function test . [ 95 ]
Side effects: Side effects are possible with any medication, including topical pain relievers. Ahmad says the most common side effect is skin irritation, which certain ingredients or preservatives ...
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