Search results
Results from the WOW.Com Content Network
Recombinant adeno-associated virus (rAAV) based genome engineering is a genome editing platform centered on the use of recombinant AAV vectors that enables insertion, deletion or substitution of DNA sequences into the genomes of live mammalian cells.
Self-complementary adeno-associated virus (scAAV) is a viral vector engineered from the naturally occurring adeno-associated virus (AAV) to be used as a tool for gene therapy. [1] Use of recombinant AAV (rAAV) has been successful in clinical trials addressing a variety of diseases. [ 2 ]
Transgene was founded in 1979, on the initiative of Pierre Chambon and Philippe Kourilsky. Jean-Pierre Lecocq was the first Scientific Director of Transgene in 1980. [2] Dr Alessandro Riva, MD, joined Transgene in 2022 as Chairman of the Board of Directors. In May 2023 the board appointed him Chairman adn Chief Executive Officer of the company ...
Because of AAV's specialized gene therapy advantages, researchers have created an altered version of AAV termed self-complementary adeno-associated virus (scAAV). Whereas AAV packages a single strand of DNA and must wait for its second strand to be synthesized, scAAV packages two shorter strands that are complementary to each other.
An American Airlines regional jet went down in the Potomac River near Washington, D.C.'s Ronald Reagan Washington National Airport after colliding with a U.S. Army Black Hawk helicopter on ...
In 1999, Wilson led a clinical trial at the Institute for Human Gene Therapy using an adenoviral vector that resulted in the death of Jesse Gelsinger.As a result, the government banned him from working on FDA-regulated human clinical trials for five years and shut down the institute, which led to a shift in his research focus towards a study of adeno-associated viruses (AAV).
WASHINGTON (Reuters) -U.S. President Donald Trump and the CEO of Nvidia Jensen Huang discussed DeepSeek - the Chinese company whose AI model's performance rocked the tech world - and tightening AI ...
He co-founded biotechnology companies active in gene therapy and AAV commercialization, [8] including AskBio (Asklepios BioPharmaceutical Inc.), a biotechnology company focused on AAV gene therapy, [9] [10] NanoCor Therapeutics, Inc. [11] Chatham Therapeutics, Inc. and Bamboo Therapeutics, Inc, spinoffs from Asklepios BioPharmaceutical Inc. [12] He was the director of the UNC School of ...