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Detailed Acyclovir dosage information for adults and children. Includes dosages for Herpes Simplex Labialis, Herpes Simplex - Suppression, Herpes Zoster and more; plus renal, liver and dialysis adjustments.
Detailed dosage guidelines and administration information for Zovirax (acyclovir). Includes dose adjustments, warnings and precautions.
Initial treatment: 200 mg PO q4hr while awake (5 times daily) for 10 days or 400 mg PO q8hr for 7-10 days. Intermittent treatment for recurrence: 200 mg PO q4hr while awake (5 times...
Generic name: acyclovir (oral) [ a-SYE-klo-veer ] Brand names: Sitavig, Zovirax. Dosage forms: buccal tablet (50 mg), oral capsule (200 mg), oral suspension (200 mg/5 mL), oral tablet (400 mg; 800 mg) Drug class: Purine nucleosides. Medically reviewed by Melisa Puckey, BPharm. Last updated on Aug 23, 2023. Uses. Warnings.
For topical dosage form (cream): For herpes simplex infection: Adults—Apply to the affected area (s), four to six times a day, for up to ten days. Children—Use and dose must be determined by your doctor. For topical dosage form (ointment): For herpes simplex infection:
The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days.
Last Update: May 7, 2023. Go to: Continuing Education Activity. Acyclovir is an agent used to treat infections caused by the herpes simplex virus (HSV). Acyclovir is FDA-approved to treat genital herpes and HSV encephalitis. Non-FDA-approved indications are mucocutaneous HSV, herpes zoster (shingles), and varicella zoster (chickenpox).
The initial recommended dose is 200 mg (one 200 mg tablet or one teaspoonful of suspension [5 mL]) three times daily. This can be increased if breakthrough occurs up to a dosage of one 200 mg tablet or one teaspoonful [5 mL] of suspension, five times daily.
CLINICAL PHARMACOLOGY. ricella-zoster virus infection. Acyclovir pharmacokinetic param. ters are. *Bioavailability decreases with increasing dose.
Acyclovir (9- [2-hydroxymethyl]guanine) is a nucleoside analog that selectively inhibits the replication of herpes simplex virus types 1 and 2 (HSV-1, HSV-2) and varicella-zoster virus (VZV). After intracellular uptake, it is converted to acyclovir monophosphate by virally-encoded thymidine kinase.