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Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina.The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts.
There are many cortical and subcortical structures implicated in urination [54] and MS lesions in various central nervous system structures can cause these kinds of symptoms. Treatment objectives are the alleviation of symptoms of urinary dysfunction, treatment of urinary infections, reduction of complicating factors and the preservation of ...
MS lesions can affect any part of the central nervous system so a person with MS can have almost any neurological signs or symptoms. [26] Fatigue is one of the most common symptoms of MS. [27] [28] Roughly 65% of people with MS experience fatigue. Of these, some 15–40% report fatigue as their most disabling symptom.
Those affected displayed symptoms such as malaise, sore throat, pain, and signs of nervous system inflammation. While its infectious nature was suspected, the exact cause remained elusive. While its infectious nature was suspected, the exact cause remained elusive.
The central component of fatigue is triggered by an increase of the level of serotonin in the central nervous system. [133] During motor activity, serotonin released in synapses that contact motor neurons promotes muscle contraction. [134] During high level of motor activity, the amount of serotonin released increases and a spillover occurs.
The following diagram is provided as an overview of and topical guide to the human nervous system: Human nervous system. Human nervous system – the part of the human body that coordinates a person's voluntary and involuntary actions and transmits signals between different parts of the body.
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...