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1-Ethynylcyclohexanol (ECX) is an alkynyl alcohol derivative which is both a synthetic precursor to, and an active metabolite of the tranquilizer ethinamate, and has similar sedative, anticonvulsant and muscle relaxant effects. It has been sold as a designer drug, first being identified in the UK in March 2012. [1] [2] [3] [4]
Ethinamate (1-ethynylcyclohexanone carbamate) is synthesized by combining acetylene with cyclohexanone to make 1-ethynylcyclohexanol, and then transforming this into a carbamate by the subsequent reaction with phosgene, and later with ammonia. Some lithium metal or similar is used to make the acetylene react with the cyclohexanone in the first ...
2 c 6 h 12 + o 2 → 2 c 6 h 11 oh This process coforms cyclohexanone , and this mixture ("KA oil" for ketone-alcohol oil) is the main feedstock for the production of adipic acid . The oxidation involves radicals and the intermediacy of the hydroperoxide C 6 H 11 O 2 H. Alternatively, cyclohexanol can be produced by the hydrogenation of phenol :
Download as PDF; Printable version; ... [1] [2] Synthesis. Clocental was first prepared by the acylation of 1-ethynylcyclohexanol with allophanyl chloride. [3] See also
Print/export Download as PDF; Printable version; In other projects Wikidata item; Appearance. move to sidebar hide ... EC 3.2.1.148: The activity is ...
tert-Amyl alcohol (TAA) or 2-methylbutan-2-ol (2M2B), is a branched pentanol. Historically, TAA has been used as an anesthetic [ 3 ] and more recently as a recreational drug . [ 4 ] TAA is mostly a positive allosteric modulator for GABA A receptors in the same way as ethanol . [ 5 ]
Suzannah Clark, a music professor at Harvard, connected the piece's resurgence in popularity to the harmonic structure, a common pattern similar to the romanesca.The harmonies are complex, but combine into a pattern that is easily understood by the listener with the help of the canon format, a style in which the melody is staggered across multiple voices (as in "Three Blind Mice"). [1]
The Billboard Hot 100 is a chart that ranks the best-performing songs in the United States. Its data is compiled by Luminate Data and published by American music magazine Billboard . The chart is based on each song's weekly physical and digital sales collectively, the amount of airplay impressions it receives on American radio stations , and ...