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Lorcaserin, marketed under the brand name Belviq, [4] [5] was a weight-loss drug developed by Arena Pharmaceuticals. It reduces appetite by activating serotonin receptor the 5-HT 2C receptor in the hypothalamus , a region of the brain which is known to control appetite. [ 6 ]
Review the prescribing information for any weight loss pill you are considering, and be sure to tell your healthcare provider about any health conditions you have as well as any medications you ...
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Weight-Loss Gimmicks That Are a Complete Scam. Mia Taylor. April 1, 2024 at 7:00 AM. Paolo Cordoni/istockphoto. ... Only a handful of weight-loss pills have been approved by the FDA. Bottom line ...
They worked primarily by suppressing appetite, and had other beneficial effects such as increased alertness. Use of amphetamines increased over the subsequent decades, including Obetrol and culminating in the "rainbow diet pill" regime. [38] This was a combination of multiple pills, all thought to help with weight loss, taken throughout the day.
The development of 5-HT 2C receptor knockout mice in the mid-1990s was a hallmark achievement in the identification and development of serotonergic drugs for weight loss. These knockout mice were hyperphagic , which led to obesity, partial Leptin resistance, increased adipose deposition, insulin resistance, and impaired glucose tolerance.
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