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They could present as the first or the only clinical manifestation of the disease. The reported prevalence of autoimmunity ranged from 14% to 54% in CVID patients and is higher for females. The most common autoimmune disorders observed in CVID are autoimmune cytopenia, idiopathic thrombocytopenic purpura (ITP), AIHA and neutropenia.
Autoimmune diseases can result in systemic or localized symptoms, depending on the given disease. [8] Typical systemic symptoms include fevers, fatigue, muscle aches, joint pain, and rashes; these can be seen in diseases such as lupus or rheumatoid arthritis. Other autoimmune diseases have localized effects on specific organ or tissue types.
Autoimmune disease Primary organ/body part affected Autoantibodies Acceptance as an autoimmune disease Prevalence rate (US) Cit. Autoimmune enteropathy: Small intestine: Anti-enterocyte antibodies Probable Rare [24] Autoimmune hepatitis: Liver: ANA, ASMA, anti-LKM1 Confirmed 1 in 10,000 to 1 in 50,000 [25] Celiac disease: Small intestine
Why women are at greater risk of autoimmune disease is a long-standing medical mystery. Researchers at Stanford University may now be a step closer to unraveling it. 4 out of 5 autoimmune disease ...
The first estimate of US prevalence for autoimmune diseases as a group was published in 1997 by Jacobson, et al. They reported US prevalence to be around 9 million, applying prevalence estimates for 24 diseases to a US population of 279 million. [73] Jacobson's work was updated by Hayter & Cook in 2012. [74]
Sex differences in medicine include sex-specific diseases or conditions which occur only in people of one sex due to underlying biological factors (for example, prostate cancer in males or uterine cancer in females); sex-related diseases, which are diseases that are more common to one sex (for example, breast cancer and systemic lupus erythematosus which occur predominantly in females); [1 ...
Data has changed throughout the course of the pandemic, as much within as between countries. However, what has remained constant is the prevalence of women affected by COVID-19 in contrast to men, although the fatalities have not been as high as theirs. [contradictory] This was especially so at the beginning of the pandemic. This might be due ...
Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system.It can contribute to the development or progression of certain conditions such as cardiovascular disease, cancer, diabetes mellitus, chronic kidney disease, non-alcoholic fatty liver disease, autoimmune and neurodegenerative ...