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  2. List of 5α-reductase inhibitors - Wikipedia

    en.wikipedia.org/wiki/List_of_5α-reductase...

    This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...

  3. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for transgender ...

  4. DHT Blockers for Hair Loss: 4 Things to Know - AOL

    www.aol.com/dht-blockers-hair-loss-4-115800682.html

    Also known by the brand name Propecia, finasteride belongs to a class of drugs called 5-alpha-reductase inhibitors. ... Natural DHT blockers, like saw palmetto and pumpkin seed oil, aren’t as ...

  5. 5α-Reductase - Wikipedia

    en.wikipedia.org/wiki/5α-Reductase

    5α-Reductase type 1 inactivated male mice have reduced bone mass and forelimb muscle grip strength, which has been proposed to be due to lack of 5α-reductase type 1 expression in bone and muscle. [29] In 5 alpha reductase type 2 deficient males, the type 1 isoenzyme is thought to be responsible for their virilization at puberty. [6]

  6. Is Post-Finasteride Syndrome Real? Plus 3 Tips for Treating ...

    www.aol.com/post-finasteride-syndrome-real-plus...

    Finasteride is a 5-alpha reductase inhibitor that’s used to treat androgenetic alopecia or androgenic alopecia (the clinical terms for male pattern baldness) and benign prostatic hyperplasia ...

  7. Dihydrotestosterone - Wikipedia

    en.wikipedia.org/wiki/Dihydrotestosterone

    A small risk of gynecomastia has been associated with 5α-reductase inhibitors (1.2–3.5%). [36] [41] Based on reports of 5α-reductase type 2 deficiency in males and the effectiveness of 5α-reductase inhibitors for hirsutism in women, reduced body and/or facial hair growth is a likely potential side effect of these drugs in men.

  8. The best hair growth products of 2024, according to experts - AOL

    www.aol.com/lifestyle/best-hair-growth-products...

    When it comes to prescription-only hair loss medications such as Finasteride, Dr. Henry tells AOL, "Finasteride and dutasteride are 5-alpha-reductase inhibitors that are often used in the ...

  9. Discovery and development of 5α-reductase inhibitors

    en.wikipedia.org/wiki/Discovery_and_development...

    The first compounds developed were selective 5-alpha reductase type 1 inhibitors, but the most potent one inhibits both type 1 and 2. The fluorine atom is an important part of the structure. [8] Benzo(f)quinolonone are also tricyclic compounds, but derivatives of the 4-azasteroid structure.