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Like many other medical conditions, obesity is the result of an interplay between environmental and genetic factors. [2] [3] Studies have identified variants in several genes that may contribute to weight gain and body fat distribution, although only in a few cases are genes the primary cause of obesity.
To date, AD-36 is the only human adenovirus that has been linked with human obesity, present in 30% of obese humans and 11% of nonobese humans. [8] In addition, a study of obese Americans indicates that about 30% of the obese individuals and only 5% of non-obese individuals have antibodies to Ad-36. [ 3 ]
In humans, the gene is located on the long arm of chromosome 7 at band 11.2 (7q11.2 [37]) and is encoded by 15 exons that extend over more than 32 kilobases. Both the 5' and the 3' untranslated regions contain introns: the 5' with two and the 3' one. Exons 1, 2 and first 89 nucleotides of exon 3 and as well as exon 15 are non-coding.
An association between viruses and obesity has been found in humans, as well as a number of different animal species. The amount that these associations may have contributed to the rising rate of obesity is yet to be determined. [5] A fat virus is the popular name for the notion that some forms of obesity in humans and animals have a viral source.
Because obesity is a complex, multifactorial condition influenced by genetics, metabolism, lifestyle, and environmental factors, he said it’s essential to work with a provider who can offer ...
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