Search results
Results from the WOW.Com Content Network
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [12] by Abraham Wald in the context of sequential tests of statistical hypotheses. [13]
Multiple definitions of the term "batch effect" have been proposed in the literature. Lazar et al. (2013) noted, "Providing a complete and unambiguous definition of the so-called batch effect is a challenging task, especially because its origins and the way it manifests in the data are not completely known or not recorded."
In medicine, a crossover study or crossover trial is a longitudinal study in which subjects receive a sequence of different treatments (or exposures). While crossover studies can be observational studies, many important crossover studies are controlled experiments, which are discussed in this article.
Particularly for array-based procedures, as mentioned above, sequences being analyzed are limited to the specific array design used. Most typical limitations to high-throughput, next generation sequencing apply. The problem of alignment accuracy to repetitive regions in the genome will result in less accurate analysis of methylation in those ...
Whereas high sequence coverage for a genome may indicate the presence of repetitive sequences (and thus be masked), for a transcriptome, they may indicate abundance. In addition, unlike genome sequencing, transcriptome sequencing can be strand-specific, due to the possibility of both sense and antisense transcripts. Finally, it can be difficult ...
Sequence alignment and analysis: Due to the unique properties of RRBS, special software is needed for alignment and analysis. [3] Using MspI to digest genomic DNA results in fragments that always start with a C (if the cytosine is methylated) or a T (if a cytosine was not methylated and was converted to a uracil in the bisulfite conversion ...
The average (mean) annual cost of raising a child across America’s 100 most populous metros is $22,989, according to an analysis by Creditnews Research of Department of Labor data. These costs ...
A pooled analysis is a statistical technique for combining the results of multiple epidemiological studies. It is one of three types of literature reviews frequently used in epidemiology, along with meta-analysis and traditional narrative reviews. Pooled analyses may be either retrospective or prospective. [1]