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There are many disease states, medical treatments and medications that put people at risk for vitamin D deficiency. Chronic diseases that increase risk include kidney and liver failure, Crohn’s disease, inflammatory bowel disease and malabsorption syndromes such as cystic fibrosis, and hyper- or hypo-parathyroidism. [24]
Extremely high levels can cause symptoms like vomiting, muscle weakness, confusion and pain, among others, according to the NIH; extremely high levels can lead to kidney failure, irregular ...
The U.S. Preventive Services Task Force say vitamin D supplements do not reduce the risk of falls or bone fractures in healthy older adults. The draft recommendation notes vitamin D can be helpful ...
AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...
Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
[9] [10] Vitamin-D supplements may not be effective in people with severe kidney disease. [11] [10] Excessive doses in humans can result in vomiting, constipation, muscle weakness, and confusion. [5] Other risks include kidney stones. [11] Doses greater than 40 000 IU (1000 μg) per day are generally required before high blood calcium occurs. [12]
The most common causes are vitamin D deficiency [47] (caused by lack of sunlight, diet or malabsorption) and chronic kidney failure. [citation needed] Vitamin D deficiency can result from malabsorption or decreased vitamin D intake such as with gastric bypass, small bowel disease, pancreatic disease, and dietary causes. [48]
Vitamin D2 vs. D3 Uses. Both vitamin D2 and vitamin D3 will help to increase vitamin D levels in the blood, says Pelitera. However, some studies have shown that supplementing vitamin D3 does a ...
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