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  2. Targeted therapy - Wikipedia

    en.wikipedia.org/wiki/Targeted_therapy

    Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, [1] others being hormonal therapy ...

  3. Targeted drug delivery - Wikipedia

    en.wikipedia.org/wiki/Targeted_drug_delivery

    Targeted delivery is believed to improve efficacy while reducing side-effects. When implementing a targeted release system, the following design criteria for the system must be taken into account: the drug properties, side-effects of the drugs, the route taken for the delivery of the drug, the targeted site, and the disease.

  4. Biological target - Wikipedia

    en.wikipedia.org/wiki/Biological_target

    The term "biological target" is frequently used in pharmaceutical research to describe the native protein in the body whose activity is modified by a drug resulting in a specific effect, which may be a desirable therapeutic effect or an unwanted adverse effect. In this context, the biological target is often referred to as a drug target.

  5. Targeted killing - Wikipedia

    en.wikipedia.org/wiki/Targeted_killing

    Modern targeted killings are frequently performed using unmanned combat aerial vehicles like the MQ-9 Reaper.. Targeted killing is a form of assassination carried out by governments outside a judicial procedure or a battlefield.

  6. Gene targeting - Wikipedia

    en.wikipedia.org/wiki/Gene_targeting

    The two most established forms of gene editing are gene-targeting and targeted-mutagenesis. While gene targeting relies on the Homology Directed Repair (HDR) (also called Homologous Recombination, HR) DNA repair pathway, targeted-mutagenesis uses Non-Homologous-End-Joining (NHEJ) of broken DNA. NHEJ is an error-prone DNA repair pathway, meaning ...

  7. Drivers targeted in emerging crime trend have one thing ... - AOL

    www.aol.com/drivers-targeted-emerging-crime...

    Texas law enforcement issued a word of warning to Ford truck owners after they arrested a trio of thieves who targeted the high-end truck model by stealing taillights.

  8. Pembrolizumab - Wikipedia

    en.wikipedia.org/wiki/Pembrolizumab

    People have had severe infusion-related reactions to pembrolizumab. There have also been severe immune-related adverse effects including lung inflammation (including fatal cases) and inflammation of endocrine organs that caused inflammation of the pituitary gland, of the thyroid (causing both hypothyroidism and hyperthyroidism in different people), and pancreatitis that caused Type 1 diabetes ...

  9. Theranostics - Wikipedia

    en.wikipedia.org/wiki/Theranostics

    These substances may include ligands of receptors present on the target tissue or compounds, like iodine, that are internalized by the target through metabolic processes. By using these mechanisms, theranostics enables the localization of pathological tissues with imaging and the targeted destruction of these tissues using high doses of radiation .