Search results
Results from the WOW.Com Content Network
Gorham's disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, [1] is a very rare skeletal condition of unknown cause.It is characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis.
Gorham's disease is a condition that targets the human musculoskeletal system including the crown of the skull. The chronic disorder involves the progressive loss of bone, although, symptoms such as intense pain are not evident during the initial stages. [ 22 ]
The condition is most common in the bones and lungs [2] and shares some characteristics with Gorham’s disease. Up to 75% of patients with lymphangiomatosis have bone involvement, leading some to conclude that lymphangiomatosis and Gorham’s disease should be considered as a spectrum of disease rather than separate diseases.
Infantile cortical hyperostosis is a self-limited condition, meaning that the disease resolves on its own without treatment, usually within 6–9 months. Long-term deformities of the involved bones, including bony fusions and limb-length inequalities, are possible but rare.
X-ray (A), CT scan (B) and MRI (C, D) show osteolysis of bone in the skull of an individual with Gorham-Stout disease. Bone remodeling is regulated by mutual cross-regulation between osteoclasts and osteoblasts. As a result, the dysfunction of CSF1R signaling directly affects the reabsorption (osteoclasts) and indirectly affects bone deposition ...
Get AOL Mail for FREE! Manage your email like never before with travel, photo & document views. Personalize your inbox with themes & tabs. You've Got Mail!
Hyperostosis is an excessive growth of bone.It may lead to exostosis.It occurs in many musculoskeletal disorders.. Disorders featuring hyperostosis include: [1] Camurati-Engelmann disease, type 2
Main page; Contents; Current events; Random article; About Wikipedia; Contact us; Donate