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Tamsulosin is a selective α 1 receptor antagonist that has preferential selectivity for the α 1A receptor in the prostate versus the α 1B receptor in the blood vessels. [ 25 ] When alpha 1 receptors in the bladder neck, prostate, ureter, and urethra are blocked, a relaxation in smooth muscle tissue results. [ 16 ]
Alpha-1 blockers are first line treatment for the symptoms of BPH in men. [1] [2] [7] [8] Doxazosin, terazosin, alfuzosin, and tamsulosin have all been well established in treatment to reduce lower urine tract symptoms (LUTS) caused by benign prostatic hyperplasia. They are all believed to be similarly effective for this purpose.
Tamsulosin: Flomax A blocker that has slight selectivity for α 1 receptors. [2] Relaxation of prostatic smooth muscle. [2] Benign prostatic hyperplasia [2] [11] Orthostatic hypotension [2] Yohimbine: Yocon Blocks α 2 receptor, and increases norepinephrine release, thus increasing CNS activity. [2] Raises blood pressure and heart rate. [2 ...
Researchers compared the findings from the participants taking terazosin, doxazosin, or alfuzosin to participants taking other prostate medications — about 437,000 taking tamsulosin and about ...
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is characterized by pelvic or perineal pain without evidence of urinary tract infection, [8] lasting longer than 3 months, [9] as the key symptom. Symptoms may wax and wane. Pain can range from mild to debilitating. Pain may radiate to the back and rectum, making sitting uncomfortable.
The way someone feels pain varies. However, one urologist can offer some common words patients with prostate cancer use to describe the bone pain that brought them to the doctor's office.
Chronic bacterial prostatitis is thought to be caused by ascending urethral infection and by reflux into the ejaculatory duct or prostatic ducts. [7] Risk factors for chronic bacterial prostatitis include functional or anatomic abnormalities, catheterization, prostate biopsy or urethritis (due to sexually transmitted infections), and unprotected penetrative anal sex. [7]
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