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2. Abituzumab - Wikipedia

   en.wikipedia.org/wiki/Abituzumab

   Abituzumab is a humanized IgG2 monoclonal antibody (mAb) targeted at CD51 (an integrin) currently in development by Merck KGaA Darmstadt, Germany in an attempt to prevent bone lesion metastases in castration-resistant prostate cancer. [1] [2]

3. Indium (111In) capromab pendetide - Wikipedia

   en.wikipedia.org/wiki/Indium_(111In)_capromab...

   Capromab is a mouse monoclonal antibody which recognizes a protein found on both prostate cancer cells and normal prostate tissue. It is linked to pendetide , a derivative of DTPA . [ 2 ] Pendetide acts as a chelating agent for the radionuclide indium-111 .

4. Tocilizumab - Wikipedia

   en.wikipedia.org/wiki/Tocilizumab

   It is a recombinant humanized monoclonal antibody of the immunoglobulin IgG1 subclass against the interleukin-6 receptor (IL-6R). [18] Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer.

5. Ponsegromab - Wikipedia

   en.wikipedia.org/wiki/Ponsegromab

   Ponsegromab (PF-06946860) is a monoclonal antibody that works as a GDF-15 inhibitor. ... pancreatic cancer, or colorectal cancer in a phase 2 clinical trial. ...

6. Ocaratuzumab - Wikipedia

   en.wikipedia.org/wiki/Ocaratuzumab

   Ocaratuzumab (AME-133v, LY2469298) is a humanized monoclonal antibody designed for the treatment of cancer and autoimmune disorders. [1] The antibody is engineered for enhanced affinity to the CD20 antigen on B-lymphocytes, increased antibody-dependent cell-mediated cytotoxicity (ADCC), and for improved treatment of low-affinity FcγRIIIa allotypes.

7. Leronlimab - Wikipedia

   en.wikipedia.org/wiki/Leronlimab

   Leronlimab (codenamed PRO 140) is a humanized monoclonal antibody targeted against the CCR5 receptor found on T lymphocytes of the human immune system.It is being investigated as a potential therapy in the treatment of COVID-19, [1] [2] triple negative breast cancer, [3] and HIV infection. [4]

8. Cancer immunotherapy - Wikipedia

   en.wikipedia.org/wiki/Cancer_immunotherapy

   Monoclonal antibodies: designed to bind to specific targets on cancer cells, marking cancer cells so that they will be better seen and destroyed by the immune system. Treatment vaccines : also known as therapeutic cancer vaccines, help the immune system learn to recognize and react to mutant proteins specific to the tumor and destroy cancer ...

9. Durvalumab - Wikipedia

   en.wikipedia.org/wiki/Durvalumab

   Durvalumab, [8] sold under the brand name Imfinzi, is an FDA-approved immunotherapy for cancer, developed by Medimmune/AstraZeneca. [9] It is a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody that blocks the interaction of programmed cell death ligand 1 with the PD-1 (CD279). [medical citation needed]