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Corneal cross-linking (CXL) with riboflavin (vitamin B 2) and UV-A light is a surgical treatment for corneal ectasia such as keratoconus, PMD, and post-LASIK ectasia. It is used in an attempt to make the cornea stronger. According to a 2015 Cochrane review, there is insufficient evidence to determine if it is useful in keratoconus. [2]
In 2016, the FDA approved corneal collagen cross-linking to halt the progression of keratoconus. [9] In some cases when the cornea becomes dangerously thin or when sufficient vision can no longer be achieved by contact lenses due to steepening of the cornea, scarring or lens intolerance, corneal cross-linking is not an option and a corneal ...
In 2002, Hafezi's clinical and research interests turned to the cornea. He became a corneal specialist, and his work helped develop the principles of corneal collagen cross-linking (CXL) and translate CXL from a laboratory into a clinical setting, initially for the treatment of keratoconus. Hafezi's combination of basic science knowledge ...
Treatment options include contact lenses and intrastromal corneal ring segments for correcting refractive errors caused by irregular corneal surface, [7] [8] corneal collagen cross-linking to strengthen a weak and ectatic cornea, [9] or corneal transplant for advanced cases.
Peter S. Hersh is an American ophthalmologist, researcher, and specialist in LASIK eye surgery, keratoconus, and diseases of the cornea.He co-authored the article in the journal Ophthalmology that presented the results of the study that led to the first approval by the U.S. Food and Drug Administration (FDA) of the excimer laser for the correction of nearsightedness in the United States.
Corneal topography showing stage II keratoconus. Computerized corneal topography can be employed for diagnostics. It is, in fact, one of the exams the patients have to undergo prior to the Cross-linking and the Mini Asymmetric Radial Keratotomy (M.A.R.K.).
[1] [2] Corneal transplantation is performed when medicines, keratoconus conservative surgery and cross-linking can no longer heal the cornea. This surgical procedure usually treats corneal blindness, [3] [4] with success rates of at least 41% as of 2021. [5] [6] [7]
Anastasios John Kanellopoulos (born in Chicago, USA) is a Greek-American eye surgeon specializing in corneal transplantation, cornea crosslinking [1] [2] [3] for keratoconus, [4] [5] complicated cataract surgery and complicated glaucoma.
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