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Crotamiton is a drug that is used both as a scabicidal (for treating scabies) and as a general antipruritic (anti-itching drug). It is a prescription, lotion-based medicine that is applied to the whole body to get rid of the scabies mite that burrows under the skin and causes itching.
Permethrin exerts its therapeutic effect by disrupting sodium transport across neuronal membranes in arthropods, inducing depolarization. This mechanism ultimately leads to respiratory paralysis in the affected arthropod, establishing permethrin as a potent agent in managing scabies and pediculosis.
European guidelines state alternatives to permethrin as including either the application of 0.2% phenothrin (washed off after two hours), or 0.5% malathion lotions (washed off after 12 hours). [2] The CDC states alternatives as topical 0.5% malathion or oral ivermectin .
“Most scabies treatments are topical medications, which are applied to the skin. Permethrin five percent cream is the most common medicine used to treat scabies. It’s applied head to toe the ...
Benzyl benzoate is an effective and inexpensive topical treatment for human scabies. [7] It has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs. [8] It is also used as an excipient in some testosterone-replacement medications (like Nebido) for treating hypogonadism. [9]
Crusted scabies may require multiple applications, or supplemental treatment with oral ivermectin (below). [15] [40] [41] Permethrin may cause slight irritation of the skin that is usually tolerable. [19] In recent years, concern is growing about permethrin-resistant scabies, [42] [43] although some researchers refer to this as pseudo ...
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