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Some have proposed that morning sickness may be useful from an evolutionary point of view. [1] Diagnosis should only occur after other possible causes have been ruled out. [3] Abdominal pain, fever, or headaches are typically not present in morning sickness. [1] Morning sickness affects about 70–80% of all pregnant women to some extent.
Researchers at Chemie Grünenthal found that thalidomide was a particularly effective antiemetic that had an inhibitory effect on morning sickness. [44] On 1 October 1957, the company launched thalidomide and began marketing it under the trade name Contergan. [45] [46] It was proclaimed a "wonder drug" for insomnia, coughs, colds and headaches ...
Feet of a baby born to a mother who had taken thalidomide while pregnant. In the late 1950s and early 1960s, the use of thalidomide in 46 countries was prescribed to women who were pregnant or who subsequently became pregnant, and consequently resulted in the "biggest anthropogenic medical disaster ever," with more than 10,000 children born with a range of severe deformities, such as ...
Previous studies have suggested sickness and nausea in pregnancy could relate to GDF15 being produced by the placenta, but researchers said the “full mechanistic understanding is lacking”.
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