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The committee found that the regular use of benzodiazepines causes the development of dependence characterized by tolerance to the therapeutic effects of benzodiazepines and the development of the benzodiazepine withdrawal syndrome including symptoms such as anxiety, apprehension, tremors, insomnia, nausea, and vomiting upon cessation of ...
Although anxiety can temporarily increase as a withdrawal symptom, there is evidence that a reduction or withdrawal from benzodiazepines can lead to a reduction of anxiety symptoms in the long run. [4] [5] Due to these increasing physical and mental symptoms from long-term use of benzodiazepines, slow withdrawal is recommended for long-term users.
Treatment for withdrawal usually involves weaning over a 3- to 21-day period if the infusion lasted for more than a week. [134] Symptoms include tremors, agitation, sleeplessness, inconsolable crying, diarrhea and sweating. In total, over fifty withdrawal symptoms are listed in this review article.
The anxiety-reducing drug, Clonazepam, has been recalled after a potentially "life-threatening" label mix-up, the Food and Drug Administration (FDA) said. According to a release from the federal ...
Restless legs syndrome can be treated using clonazepam as a third-line treatment option, as the use of clonazepam is still investigational. [35] [36] Bruxism also responds to clonazepam in the short term. [37] REM sleep behavior disorder responds well to low doses of clonazepam. [38] It is also used for:
Clonazepam, an anxiety drug, is being voluntarily recalled for the potential to cause a “life-threatening” event. ... The oral medication is commonly used to provide “a calming effect on the ...
There is some evidence that a prior history of CNS depressant dependence (e.g. alcohol) increases the risk of dependence on benzodiazepines. Tolerance to drugs is commonly believed to be due to receptor down-regulation; however, there is very limited evidence to support this, and this hypothesis comes from animal studies using very high doses.
“The brain changes, and it doesn’t recover when you just stop the drug because the brain has been actually changed,” Kreek explained. “The brain may get OK with time in some persons. But it’s hard to find a person who has completely normal brain function after a long cycle of opiate addiction, not without specific medication treatment.”