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Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1] Most infections show no symptoms, in which case it is known as latent tuberculosis . [ 1 ] Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. [ 1 ]
The main result was a relative risk (RR) of 0.40 (95% confidence interval (CI) 0.31 to 0.52) for development of active tuberculosis over two years or longer for patients treated with INH, with no significant difference between treatment courses of six or 12 months (RR 0.44, 95% CI 0.27 to 0.73 for six months, and 0.38, 95% CI 0.28 to 0.50 for ...
Active tuberculosis can be contagious while latent tuberculosis is not, and it is therefore not possible to get TB from someone with latent tuberculosis. The main risk is that approximately 10% of these people (5% in the first two years after infection and 0.1% per year thereafter) will go on to develop active tuberculosis.
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Official figures from the UK Health Security Agency (UKHSA) show that cases of tuberculosis increased by 11 per cent by the end of last year, with nearly 5,000 people diagnosed with the disease.
The individuals to whose entries this category is appended have tuberculosis indicated as the cause of death and from its complications, and tuberculous meningitis. Subcategories This category has the following 3 subcategories, out of 3 total.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Because MDR tuberculosis is an airborne pathogen, persons with active, pulmonary tuberculosis caused by a multidrug-resistant strain can transmit the disease if they are alive and coughing. [41] TB strains are often less fit and less transmissible, and outbreaks occur more readily in people with weakened immune systems (e.g., patients with HIV ).